Drugs by Approval Status
Browse medications in the VitalsCentral database grouped by their regulatory and clinical status. Jump to a status to see the drugs it currently contains, then follow a card for full clinical information. Looking for a name instead? Use the Drugs A-Z index.
38 drugs
Medications that have received marketing approval from the U.S. Food and Drug Administration (FDA).
Albuterol
Ventolin, ProAir, Proventil
Selective beta-2 adrenergic receptor agonist. Relaxes bronchial smooth muscle by activating adenylyl cyclase, increasing intracellular cAMP, leading to bronchodilation.
Amlodipine
Norvasc, Istin, Amlong
Inhibits calcium ion influx across cell membranes of cardiac and vascular smooth muscle cells, resulting in peripheral arterial vasodilation and reduced blood pressure.
Amoxicillin
Amoxil, Trimox, Moxatag
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing cross-linking of peptidoglycan chains essential for cell wall strength.
Atenolol
Tenormin
Atenolol is a cardioselective beta-1 adrenergic receptor blocker used to treat hypertension, angina, and certain arrhythmias.
Atorvastatin
Lipitor
Atorvastatin is an HMG-CoA reductase inhibitor (statin) used to lower cholesterol and reduce cardiovascular disease risk. One of the most prescribed medications worldwide.
Azithromycin
Zithromax, Z-Pack, Azithrocin
Macrolide antibiotic effective against a broad range of bacterial infections including respiratory, skin, and sexually transmitted infections.
Cephalexin
Keflex
Cephalexin is a first-generation oral cephalosporin antibiotic used to treat susceptible bacterial infections of the skin, respiratory tract, urinary tract, and bone.
Ciprofloxacin
Cipro
Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic used to treat a variety of bacterial infections including urinary tract, respiratory, gastrointestinal, and skin infections.
Citalopram
Celexa
Citalopram is a selective serotonin reuptake inhibitor (SSRI) antidepressant used to treat major depressive disorder.
Clopidogrel
Plavix
Clopidogrel is a thienopyridine antiplatelet agent used to reduce atherothrombotic events in patients with acute coronary syndrome, recent myocardial infarction or stroke, and peripheral arterial disease.
Doxycycline
Vibramycin, Doryx, Oracea
Doxycycline is a broad-spectrum tetracycline antibiotic used to treat respiratory, skin, genital, and tick-borne infections, and as prophylaxis for malaria.
Duloxetine
Cymbalta, Irenka
Serotonin-norepinephrine reuptake inhibitor (SNRI) used for depression, anxiety, diabetic neuropathy, fibromyalgia, and chronic musculoskeletal pain.
Escitalopram
Lexapro, Cipralex
Selective serotonin reuptake inhibitor (SSRI). Potently and selectively inhibits neuronal reuptake of serotonin (5-HT), enhancing serotonergic neurotransmission.
Fluoxetine
Prozac, Sarafem
Selective serotonin reuptake inhibitor (SSRI) and the first drug in its class, widely used for depression, OCD, and eating disorders.
Furosemide
Lasix
Furosemide is a potent loop diuretic used to treat fluid overload and edema associated with heart failure, renal disease, and hepatic cirrhosis, and to manage hypertension.
Gabapentin
Neurontin, Gralise, Horizant
Binds to alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing excitatory neurotransmitter release. Exact mechanism not fully understood.
Hydrochlorothiazide
Microzide, HydroDIURIL
Thiazide diuretic used to treat hypertension and edema by reducing sodium and water reabsorption in the kidneys.
Levothyroxine
Synthroid, Levoxyl, Euthyrox +1
Synthetic form of endogenous thyroid hormone T4. Converted to T3 (active form) in peripheral tissues. Binds to thyroid hormone receptors, regulating gene expression for metabolism, growth, and develop
Linagliptin
Tradjenta, Trajenta
DPP-4 inhibitor for type 2 diabetes. Unique among gliptins for primarily non-renal elimination, requiring no dose adjustment in kidney disease.
Lisinopril
Zestril, Prinivil, Qbrelis
Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor used to treat hypertension, heart failure, and improve survival after myocardial infarction.
Losartan
Cozaar, Lortaan
Selectively blocks binding of angiotensin II to AT1 receptors, producing vasodilation, reduced aldosterone secretion, and decreased blood pressure.
Metformin
Glucophage, Fortamet, Glumetza +1
Metformin is a biguanide antidiabetic agent used as first-line therapy for type 2 diabetes mellitus. It works primarily by decreasing hepatic glucose production and improving insulin sensitivity.
Metoprolol
Lopressor, Toprol-XL, Betaloc
Selective beta-1 adrenergic receptor blocker. Reduces heart rate, myocardial contractility, and cardiac output, lowering blood pressure and myocardial oxygen demand.
Montelukast
Singulair
Leukotriene receptor antagonist used for asthma maintenance and allergic rhinitis.
Omeprazole
Prilosec, Losec, Omesec
Irreversibly blocks the hydrogen/potassium adenosine triphosphatase enzyme system (H+/K+ ATPase or gastric proton pump) of the gastric parietal cell, suppressing gastric acid secretion.
Pantoprazole
Protonix, Pantoloc
Proton pump inhibitor for gastric acid suppression, used in GERD, erosive esophagitis, and Zollinger-Ellison syndrome.
Prednisone
Deltasone, Rayos, Sterapred
Synthetic corticosteroid prodrug converted to prednisolone (active form) in the liver. Binds to glucocorticoid receptors, modulating gene transcription to reduce inflammation and suppress immune respo
Rosuvastatin
Crestor, Ezallor
Rosuvastatin is a potent HMG-CoA reductase inhibitor (statin) used to lower LDL cholesterol and reduce cardiovascular risk.
Sertraline
Zoloft
Sertraline is a selective serotonin reuptake inhibitor (SSRI) antidepressant used to treat major depressive disorder, panic disorder, OCD, PTSD, social anxiety disorder, and premenstrual dysphoric disorder.
Simvastatin
Zocor, FloLipid
Simvastatin is an HMG-CoA reductase inhibitor (statin) used to lower LDL cholesterol and triglycerides and to reduce the risk of cardiovascular events.
Tramadol
Ultram, ConZip
Tramadol is a centrally acting opioid analgesic with additional serotonin and norepinephrine reuptake inhibition, used for moderate to moderately severe pain.
Venlafaxine
Effexor, Effexor XR
Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, and panic disorder.
Warfarin
Coumadin, Jantoven
Warfarin is an oral vitamin K antagonist anticoagulant used to prevent and treat thromboembolic disorders such as venous thromboembolism and stroke in atrial fibrillation.
Medications available without a prescription in one or more markets.
Acetaminophen
Tylenol, Panadol
Acetaminophen is a widely used non-opioid analgesic and antipyretic for the relief of mild to moderate pain and fever. It has little anti-inflammatory activity.
Aspirin
Bayer, Ecotrin, Bufferin
Aspirin is a salicylate NSAID with analgesic, antipyretic, anti-inflammatory, and antiplatelet properties, widely used for pain, fever, and cardiovascular prevention.
Cetirizine
Zyrtec, Reactine, Alerid
Second-generation antihistamine used for allergic rhinitis and chronic urticaria with minimal sedation.
Ibuprofen
Advil, Motrin, Nurofen
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief, fever reduction, and anti-inflammatory effects. Available over-the-counter and by prescription.
Naproxen
Aleve, Naprosyn, Anaprox
Naproxen is a propionic-acid non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever.