Proton Pump Inhibitors

Agents that suppress gastric acid secretion by inhibiting the gastric H+/K+ ATPase.

2 drugs in this class

Drugs in Proton Pump Inhibitors

Omeprazole

Prilosec, Losec, Omesec

Irreversibly blocks the hydrogen/potassium adenosine triphosphatase enzyme system (H+/K+ ATPase or gastric proton pump) of the gastric parietal cell, suppressing gastric acid secretion.

Proton Pump InhibitorsSmall Molecule

Indications: Gastroesophageal reflux disease (GERD), Peptic ulcer disease...

Pantoprazole

Protonix, Pantoloc

FDA Approved

Proton pump inhibitor for gastric acid suppression, used in GERD, erosive esophagitis, and Zollinger-Ellison syndrome.

Proton Pump InhibitorsSmall Molecule

Indications: Gastroesophageal reflux disease (GERD), Erosive esophagitis...

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